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U.S. Department of Energy
Office of Scientific and Technical Information

Exposure of F344 rats to aerosols of {sup 239}PuO{sub 2} and chronically inhaled cigarette smoke

Technical Report ·
OSTI ID:54804

Nuclear workers may be accidently exposed to radioactive materials such as {sup 239}PuO{sub 2} by inhalation, and thus have increased risk for lung cancer compared to the general population. Of additional concern is the possibility that interactions between radionuclides and other carcinogens may increase the risk of cancer induction. An important and common lung carcinogen is cigarette smoke. This study is being conducted to better determine the combined effects of inhaled {sup 239}PuO{sub 2} and cigarette smoke on the induction of lung cancer in rats.

Research Organization:
Lovelace Biomedical and Environmental Research Inst., Albuquerque, NM (United States). Inhalation Toxicology Research Inst.
DOE Contract Number:
AC04-76EV01013
OSTI ID:
54804
Report Number(s):
ITRI--144; ON: DE95007526
Country of Publication:
United States
Language:
English