BEIR-IV: The effects on populations of exposure to internally deposited alpha-emitting radionuclides, 1987: Health risks of radon and other internally deposited alpha-emitters

Technical Report · Tue Sep 01 04:00:00 EDT 1987

OSTI ID:5477779

Fabrikant, J I

This report attempts to respond to a broad range of scientific questions that impact current public health issues; not all of these questions can be addressed adequately with currently available information. There is considerable variation in the amount of data from epidemiologic studies of human populations and from experimental animal investigations that are available for each radionuclide. For certain of the alpha-emitting radionuclides, such as radon and its daughters, radium and thorium, human epidemiological data are available. For others, however, such as the transuranic elements, some useful information is available on humans; accordingly, dependence must be placed on extensive experiments with animals. As in all experimental studies with animals, the extent to which the information and conclusions can be extrapolated to humans and the confidence that can be placed on such an extrapolation remain uncertain. Where human data are available, wherever possible the Committee has relied on its own analyses using current epidemiological methods to address these problems rather than relying solely on published information. The Committee has also explored statistical methods for analysis of interspecies comparisons of the risks from different radionuclides where useful animal data are available and the human data are limited.

• Research Organization: Lawrence Berkeley Lab., CA (USA)
• DOE Contract Number: AC03-76SF00098
• OSTI ID: 5477779
• Report Number(s): LBL-24173; ON: DE88004897
• Country of Publication: United States
• Language: English

Related Subjects

560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDES
ALKALINE EARTH METALS
ALPHA DECAY RADIOISOTOPES
ALPHA DOSIMETRY
DAUGHTER PRODUCTS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
DOSIMETRY
ELEMENTS
EVALUATION
FLUIDS
GASES
HAZARDS
HEALTH HAZARDS
HUMAN POPULATIONS
INTERNAL IRRADIATION
IRRADIATION
ISOTOPES
MATHEMATICAL MODELS
METALS
NEOPLASMS
NONMETALS
POLONIUM
POPULATIONS
RADIOISOTOPES
RADIONUCLIDE KINETICS
RADIUM
RADON
RARE GASES
RISK ASSESSMENT
THORIUM
TRANSURANIUM ELEMENTS
URANIUM