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Assessment of skin ulcer healing capability by technetium-99m phosphate angiogram and blood-pool images

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:5476429
; ; ; ; ;
The accuracy of radionuclide angiography and blood-pool imaging using (/sup 99m/Tc)-phosphate to assess skin ulcer perfusion as an indicator of healing capacity was determined in 50 studies performed on 45 patients with nonhealing ulcers of the lower extremities. Two nuclear medicine physicians without clinical bias, graded the perfusion of the ulcer on the images as normal, increased or reduced with respect to the opposite limb. Patients were followed closely with aggressive local wound care for at least 14 days. Of the 31 ulcers which healed, the radionuclide study correctly predicted 30; of the 19 ulcers which did not heal, 14 were correctly predicted. Eight patients had osteomyelitis; four of those healed and four did not. The radionuclide study predicted healing in seven. This technique is a simple, reliable way to predict the microcirculatory adequacy for ulcer healing. Specificity is diminished in the presence of osteomyelitis.
Research Organization:
Univ. of Utah, Salt Lake City
OSTI ID:
5476429
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 26:6; ISSN JNMEA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BIOMEDICAL RADIOGRAPHY
BLOOD CIRCULATION
BODY
BODY AREAS
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
DYNAMIC FUNCTION STUDIES
HEALING
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIMBS
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OSTEOMYELITIS
OXYGEN COMPOUNDS
PATHOLOGICAL CHANGES
PATIENTS
PHOSPHATES
PHOSPHORUS COMPOUNDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RECOVERY
REFRACTORY METAL COMPOUNDS
SCINTISCANNING
SKELETAL DISEASES
SKIN
TECHNETIUM 99
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TECHNETIUM PHOSPHATES
TRANSITION ELEMENT COMPOUNDS
ULCERS
YEARS LIVING RADIOISOTOPES