Retinopathy following radiation therapy of paranasal sinus and nasopharyngeal carcinoma

Journal Article · · Retina; (United States)

DOI:https://doi.org/10.1097/00006982-198700730-00002· OSTI ID:5467625

Midena, E; Segato, T; Piermarocchi, S; Corti, L; Zorat, P L; Moro, F

Radiation retinopathy is a complication of the therapeutic irradiation of orbital and periorbital structures. The authors studied two groups of patients who had orbital (group 1) and periorbital (group 2) external irradiation. Radiation retinopathy occurred in 63.6% of patients in group 1 and 36.3% group 2. Retinal radiation damage showed a different clinical evaluation in the two groups, appearing earlier (mean, 11 versus 55 months) and with greater involvement of the peripheral retina in group 1 (with three cases of neovascular glaucoma). This study demonstrates that radiation retinopathy occurs in a significant number of cases when the eye is not totally involved in the irradiation field and shows at least two different clinical aspects in relation to the radiation treatment. It also suggests that portal design and choroidal circulation damage may represent important factors in the development of radiation retinopathy.

• Research Organization: Univ. of Padova, Italy
• OSTI ID: 5467625
• Journal Information: Retina; (United States), Journal Name: Retina; (United States) Vol. 7:3; ISSN RETID
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CARCINOMAS
DISEASES
EYES
FACE
HEAD
INJURIES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
RETINA
SENSE ORGANS
SENSE ORGANS DISEASES
SIDE EFFECTS
SINUSES
THERAPY