Does the corticoadrenal adenoma with ''pre-Cushing's syndrome'' exist

Journal Article · Tue Dec 01 00:00:00 EST 1981 · J. Nucl. Med.; (United States)

OSTI ID:5466205

Charbonnel, B; Chatal, J F; Ozanne, P

An adrenal tumor was discovered fortuitously in a patient with no clinical features of Cushing's syndrome. On adrenal imaging, there was good uptake in the nodule but no visualization of the contralateral adrenal. The latter was seen, however, in a second scan performed under ACTH treatment. In the hormone assessment, basal cortisol and 17-hydroxycorticoids were normal and cortisol diurnal variation was near normal, but a dexamethasone suppression test and ACTH responses to metyrapone and insulin hypoglycemia were abnormal. Eight months after excision of a spongiocytic-type adenoma, the remaining adrenal was visible on scintigram and the hormonal tests were normal. This pattern suggests that the clinical Cushing's syndrome was enough to partially suppress ACTH and, consequently, visualization of the contralateral gland.

• Research Organization: Departement d'Endocrinologie, Clinique Medicale B, Hotel-Dieu, Nantes, France
• OSTI ID: 5466205
• Journal Information: J. Nucl. Med.; (United States), Vol. 22:12
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
SCINTISCANNING
ADRENAL GLANDS
ACTH
CORTICOSTEROIDS
CUSHING SYNDROME
HYDROCORTISONE
IMAGES
PATIENTS
ADRENAL HORMONES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
GLUCOCORTICOIDS
HORMONES
HYDROXY COMPOUNDS
KETONES
NEOPLASMS
ORGANIC COMPOUNDS
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
PREGNANES
RADIOISOTOPE SCANNING
STEROID HORMONES
STEROIDS
550601* - Medicine- Unsealed Radionuclides in Diagnostics