Screening for breast cancer in a high-risk series
A unique cohort of women at increased risk of breast cancer because of prior X-ray treatment of acute mastitis and their selected high-risk siblings were offered periodic breast cancer screening including physical examination of the breasts, mammography, and thermography. Twelve breast cancers were detected when fewer than four would have been expected based on age-specific breast cancer detection rates from the National Cancer Institute/American Cancer Society Breast Cancer Demonstration Detection Projects. Mammography was positive in all cases but physical examination was positive in only three cases. Thermography was an unreliable indicator of disease. Given the concern over radiation-induced risk, use of low-dose technique and of criteria for participation that select women at high risk of breast cancer will maximize the benefit/risk ratio for mammography screening.
- OSTI ID:
- 5463196
- Journal Information:
- J. Surg. Oncol.; (United States), Vol. 19:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
MAMMARY GLANDS
BIOMEDICAL RADIOGRAPHY
DELAYED RADIATION EFFECTS
THERMOGRAPHY
NEOPLASMS
RADIOINDUCTION
RISK ASSESSMENT
SCREENING
WOMEN
X RADIATION
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTROMAGNETIC RADIATION
FEMALES
GLANDS
IONIZING RADIATIONS
MAMMALS
MAN
MEASURING METHODS
MEDICINE
NUCLEAR MEDICINE
ORGANS
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOLOGY
VERTEBRATES
560151* - Radiation Effects on Animals- Man
550602 - Medicine- External Radiation in Diagnostics- (1980-)