Absorption and turnover rates of manganese in the chick

Conference · Sat Mar 01 04:00:00 EST 1986 · Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)

OSTI ID:5462147

Halpin, K M; Baker, D H

Experiments were conducted with young chicks to assess the absorption and turnover rates of manganese (Mn), using tissue Mn accumulation as the response criterion. To estimate Mn absorption efficiency, chicks were injected intraperitoneally (IP) or crop intubated twice daily with three levels of inorganic Mn (provided as MnSo/sub 4/ H/sub 2/O). All chicks were fed a Mn-deficient (1.4 mg/kg) casein-dextrose diet during this 14-day period. Tibia Mn concentration was regressed on Mn intake (r/sup 2/ = 0.99) and the two routes (IP injection and crop intubation) of Mn administration were compared using the slope-ratio technique. The absorption efficiency of crop-intubated Mn was 2.40%. To estimate turnover rates of Mn in avian tissues, chicks were serially killed following a period of Mn loading (fed 2000 mg/kg Mn for 14 days). The log of tissue Mn concentration was regressed on depletion time, and biological half-life was determined. The half-life of Mn in tibia, pancreas, and bile was 6.0, 7.3, and 1.1 days, respectively. These data suggest that the avian's relatively high dietary requirement for Mn cannot be explained by inefficient gut absorption, but instead by a more rapid turnover of body Mn relative to that which occurs in mammalian species.

• Research Organization: Univ. of Illinois, Urbana
• OSTI ID: 5462147
• Report Number(s): CONF-8604222-
• Conference Information: Journal Name: Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States) Journal Volume: 45:3
• Country of Publication: United States
• Language: English

Related Subjects

550500* -- Metabolism
59 BASIC BIOLOGICAL SCIENCES
ABSORPTION
ANIMALS
BILE
BIOLOGICAL ACCUMULATION
BIOLOGICAL HALF-LIFE
BIOLOGICAL MATERIALS
BIRDS
BODY
BODY FLUIDS
CHICKENS
DIET
DIGESTIVE SYSTEM
DISTRIBUTION
ELEMENTS
ENDOCRINE GLANDS
FOWL
GLANDS
INJECTION
INTAKE
INTESTINAL ABSORPTION
INTRAPERITONEAL INJECTION
MANGANESE
MATERIALS
METABOLISM
METALS
ORGANS
PANCREAS
SKELETON
TIBIA
TISSUE DISTRIBUTION
TRANSITION ELEMENTS
UPTAKE
VERTEBRATES