Relative decreased splenic uptake of Tc-99m-sulfur colloid in patients with pancreatic carcinoma

Journal Article · Fri Jan 01 00:00:00 EST 1982 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198201000-00001· OSTI ID:5450956

Tatum, J L; Burke, T S; Fratkin, M J; Sharpe, Jr, A R; Goodrich, J K

Relative spleen/liver activity ratio was determined from posterior projection images using a photodensitometric method. Ratios from scans of 22 patients with proven pancreatic carcinoma (12 from rectilinear scans and 10 from scintillation camera images) were determined and compared to studies from patients documented as normal and to randomly selected liver/spleen imaging studies which had been previously interpreted as normal. The mean ratio from the pancreatic carcinoma group was significantly lower than the means of the respective normal groups (p(t) less than .0001 for rectilinear scans and p(t) less than .001 for scintigrams). There was no significant difference between the means of the proven normal and randomly selected normal groups or between the two pancreatic carcinoma groups. Splenic vascular alteration is discussed as a possible reason for decreased splenic distribution of Tc-99m-sulfur colloid in this patient group.

• Research Organization: Department of Radiology, Virginia Commonwealth University, Medical College of Virginia, Richmond
• OSTI ID: 5450956
• Journal Information: Clin. Nucl. Med.; (United States), Vol. 7:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
PANCREAS
NEOPLASMS
ADOLESCENTS
CHILDREN
ELDERLY PEOPLE
HUMAN POPULATIONS
ISOMERIC NUCLEI
LIVER
PATIENTS
SCINTISCANNING
SPLEEN
TECHNETIUM 99
UPTAKE
AGE GROUPS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE GLANDS
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MINORITY GROUPS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
POPULATIONS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics