Oral verrucous carcinoma. Treatment with radiotherapy

Journal Article · Mon Feb 01 00:00:00 EST 1988 · Cancer (Philadelphia); (United States)

DOI:https://doi.org/10.1002/1097-0142(19880201)61:3<458::AID-CNCR2820610309>3.0.CO;2-T· OSTI ID:5442524

Nair, M K; Sankaranarayanan, R; Padmanabhan, T K; Madhu, C S

Fifty-two cases of oral verrucous carcinoma treated with radiotherapy at the Regional Cancer Centre, Trivandrum, Kerala, India in 1982 were evaluated to determine the distribution within the oral cavity, clinical extent, and effectiveness of radiotherapy in controlling the disease. The most common site was the buccal mucosa. Fifty percent of the patients had clinically negative regional lymph nodes and 33% were in earlier stages (T1, T2, N0, and M0). The overall 3-year no evidence of disease (NED) survival rate was 44%. The 3-year NED survival rate with radium implant was 86%. We cannot comment on anaplastic transformation after radiotherapy because our treatment failures have not been subjected for biopsy concerning this matter. Because the results are comparable with those of well-differentiated squamous cell carcinoma, we think that the treatment policies advocated for oral squamous cell carcinoma are also applicable to oral verrucous carcinoma.

• Research Organization: Medical College Campus, Trivandrum, Kerala (India)
• OSTI ID: 5442524
• Journal Information: Cancer (Philadelphia); (United States), Vol. 61:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
RADIOTHERAPY
ORAL CAVITY
DOSE-RESPONSE RELATIONSHIPS
INDIA
PATIENTS
RADIATION SOURCE IMPLANTS
RADIUM
SURVIVAL CURVES
ALKALINE EARTH METALS
ASIA
DEVELOPING COUNTRIES
DIGESTIVE SYSTEM
DISEASES
ELEMENTS
IMPLANTS
MEDICINE
METALS
NEOPLASMS
NUCLEAR MEDICINE
RADIATION SOURCES
RADIOLOGY
THERAPY
550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)