Effect of cadmium chloride on thyroid activity of the female Indian palm squirrel, Funambulus pennanti (Wroughton)

Journal Article · Mon Feb 01 00:00:00 EST 1988 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01881050· OSTI ID:5440078

Shrivastava, V K; Sathyanesan, A G

In humans, exposure to Cadmium (Cd) occurs primarily through inhalation and ingestion. Acute Cd inhalation results in pulmonary edema and respiratory tract irritation; while chronic inhalation causes fibrotic and emphysematous changes in lung tissue as well as damage of renal proximal tubules. Several workers have reviewed the toxic effects of Cd on mammals, including man. In laboratory animals Cd produced kidney damage, testicular necrosis and atrophy, brain hemorrhage, hypertension, liver damage and reduced growth. It also induced changes in the adrenal and thyroid gland in the rat. In this study, squirrels, Funambulus pennanti, were administered a single dose of CdCl/sub 2/ intraperitoneally, and their thyroid structure and radioiodine I/sup 131/ uptake were assessed.

• Research Organization: Banaras Hindu Univ., Varanasi, India
• OSTI ID: 5440078
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Vol. 40:2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
CADMIUM CHLORIDES
BIOLOGICAL EFFECTS
IODINE 131
UPTAKE
THYROID
MORPHOLOGICAL CHANGES
ENZYME ACTIVITY
SQUIRRELS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CADMIUM COMPOUNDS
CADMIUM HALIDES
CHLORIDES
CHLORINE COMPOUNDS
DAYS LIVING RADIOISOTOPES
ENDOCRINE GLANDS
GLANDS
HALIDES
HALOGEN COMPOUNDS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
RODENTS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology
550601 - Medicine- Unsealed Radionuclides in Diagnostics