Mus spretus LINE-1s in the Mus musculus domesticus inbred strain C57BL/6J are from two different Mus spretus LINE-1 subfamilies
Journal Article
·
· Genetics
OSTI ID:543051
- Univ. of Texas Health Science Center, San Antonio, TX (United States)
A LINE-1 element, L1C105, was found in the Mus musculus domesticus inbred strain, C57BL/6J. Upon sequencing, this element was found to belong to a M. spretus LINE-1 subfamily originating within the last 0.2 million years. This is the second spretus-specific LINE-1 subfamily found to be represented in C57BL/6J. Although it is unclear how these M. spretus LINE-1s transferred from M. spretus to M. m. domesticus, it is now clear that at least two different spretus LINE-1 sequences have recently transferred. The limited divergence between the C57BL/6J spretus-like LINE-1s and their closest spretus ancestors suggests that the transfer did not involve an exceptionally long lineage of sequential transpositions. 54 refs., 6 figs.
- OSTI ID:
- 543051
- Journal Information:
- Genetics, Journal Name: Genetics Journal Issue: 2 Vol. 142; ISSN GENTAE; ISSN 0016-6731
- Country of Publication:
- United States
- Language:
- English
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