Correlation of trace elements in hair with colon cancer
The trace element content of 116 hair samples from patients with colon cancer and from referent series of patients who had a variety of other diseases were measured using proton-induced x-ray emission (PIXE). The patients had been on largely uncontrolled diets, and the interest was whether there were differences in trace element concentrations attributable to the effects of colon cancer. The concentrations of K, Ca, Mn, Fe, Cu, Zn, Se, Br, and Rb were determined using a beam of 2.5-MeV protons. Minimum detectable limits (MDL) of 0.3 ppM were obtained for Zn and Se. Cluster analysis of the data set did not reveal any significant differences between the cancer and control groups. Mean values and ranges obtained for the elemental concentrations show good agreement with other published determinations. 20 refs., 3 figs., 3 tabs.
- Research Organization:
- Brookhaven National Lab., Upton, NY (USA); New York Univ., NY (USA). Medical Center
- DOE Contract Number:
- AC02-76CH00016
- OSTI ID:
- 5430131
- Report Number(s):
- BNL-38355; CONF-8606181-4; ON: DE86014172
- Resource Relation:
- Conference: 4. international conference on particle induced X-ray emission and its analytical applications, Tallahassee, FL, USA, 9 Jun 1986
- Country of Publication:
- United States
- Language:
- English
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SIMULTANEOUS DETERMINATION OF 30 TRACE ELEMENTS IN CANCEROUS AND NON- CANCEROUS HUMAN TISSUE SAMPLES WITH GAMMA-RAY SPECTROMETRY
Related Subjects
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
HAIR
X-RAY SPECTROSCOPY
BROMINE
CALCIUM
COPPER
CORRELATIONS
DIET
IRON
LARGE INTESTINE
MANGANESE
NEOPLASMS
POTASSIUM
RUBIDIUM
SELENIUM
ZINC
ALKALI METALS
ALKALINE EARTH METALS
BODY
DIGESTIVE SYSTEM
DISEASES
ELEMENTS
GASTROINTESTINAL TRACT
HALOGENS
INTESTINES
METALS
NONMETALS
ORGANS
SEMIMETALS
SKIN
SPECTROSCOPY
TRANSITION ELEMENTS
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
400104 - Spectral Procedures- (-1987)