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Mutagenicity of airborne particles in relation to traffic and air pollution parameters

Journal Article · · Environ. Sci. Technol.; (United States)
DOI:https://doi.org/10.1021/es00098a010· OSTI ID:5429117
 [1]; ; ;
  1. Central Inst. for Industrial Research, Oslo, Norway
The mutagenicity of airborne particlulate matter in samples taken at street and roof levels has been compared by the Salmonella/microsome assay. Only extracts of particles less than 3 ..mu..m in diameter showed mutagenic activity. The mutagenic activity of street samples was enhanced in the presence of liver microsomes, whereas the activity of roof samples was independent of S9 addition. The activity of roof samples in the presence of S9 was 5-25% of the activity of the corresponding street samples. The mutagenic activity of street samples varied with traffic intensity as did the concentration of air pollution parameters, such as CO, NO, and polycyclic aromatic hydrocarbons (PAHs). A 15-35% reduction in activity from day to night was observed for street samples, but not for roof samples. The mutagenic activity of street samples was mainly associated with polycyclic aromatic compounds. Some activity was found in an acidic fraction.
OSTI ID:
5429117
Journal Information:
Environ. Sci. Technol.; (United States), Journal Name: Environ. Sci. Technol.; (United States) Vol. 16:4; ISSN ESTHA
Country of Publication:
United States
Language:
English