Effects of 2. 45 GHz microwave radiation on the development of Japanese quail cerebellum

Journal Article · Mon Feb 01 04:00:00 EST 1982 · Teratology; (United States)

OSTI ID:5424636

Inouye, M; Galvin, Jr, M J; McRee, D I

Fertilized Japanese quail eggs were continuously exposed to 2.45 GHz microwave radiation from day 1 through day 12 of incubation at a power density of 5.0 +/- 0.52 mW/cm2 (mean specific absorption rate . 4.03 mW/gm). In the experiment with embryos, irradiated and control embryos were removed from eggs on day 12, 13 or 14 of incubation and the cerebella were histologically examined. In order to examine the long-term effect of microwave radiation during embryogenesis on the cerebellum, some of the quail were allowed to hatch and were reared to eight weeks of age. Their cerebella were histologically examined, and the extent of dendritic arbores, the length of the stem of the primary dendrite, and the size of the perikaryon of Purkinje cells were measured in Golgi-Cox impregnated sections. In the irradiated embryos, a slight developmental retardation was found in the cerebellar cortices in terms of several morphological parameters. The effects included the growth and subsequent decline of the external granular layer, the growth of the molecular layer, the cellular differentiation and the alignment of Purkinje cells, and the accumulation of granule cells beneath the Purkinje cell layer, as well as lower body and brain weights. In the eight-week-old quail, no significant differences were noted between irradiated and control cerebella in the morphological measurements of Purkinje cells.

• Research Organization: Laboratory of Environmental Biophysics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina
• OSTI ID: 5424636
• Journal Information: Teratology; (United States), Journal Name: Teratology; (United States) Vol. 25:1; ISSN TJADA
• Country of Publication: United States
• Language: English

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560400* -- Other Environmental Pollutant Effects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIRDS
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CEREBELLUM
COSMIC RADIO SOURCES
EGGS
ELECTROMAGNETIC RADIATION
EMBRYOS
H2 REGIONS
HISTOLOGY
MICROWAVE RADIATION
MORPHOLOGICAL CHANGES
NERVOUS SYSTEM
ONTOGENESIS
ORGANS
RADIATIONS
VERTEBRATES