Normal cerebrospinal fluid dynamics. A study with intraventricular injection of sup 111 In-DTPA in leukemia and lymphoma without meningeal involvement

Journal Article · Fri Sep 01 00:00:00 EDT 1989 · Archives of Neurology; (USA)

DOI:https://doi.org/10.1001/archneur.1989.00520450067021· OSTI ID:5411244

Haaxma-Reiche, H; Piers, A; Beekhuis, H ^[1]

---

1. Univ. of Groningen (Netherlands)

The cerebrospinal fluid flow pattern in seven patients with leukemia or lymphoma, but without prior meningeal or cerebral disease, was studied following introduction of indium-diethylenetriamine pentaacetic acid In-DTPA 111 in a lateral ventricle through an Ommaya reservoir. The time to egress from the ventricular system into the basal cisterns was variable but generally short. One hour after administration, the basal cisterns were clearly visible in all patients. Thereafter, kinetics throughout the cranial and spinal subarachnoid space were consistent. The flow patterns of three patients cured of meningeal dissemination and one patient with mild meningeal leukemia were similar to the normal pattern.

• OSTI ID: 5411244
• Journal Information: Archives of Neurology; (USA), Journal Name: Archives of Neurology; (USA) Vol. 46:9; ISSN 0003-9942; ISSN ARNEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY FLUIDS
CARBOXYLIC ACIDS
CEREBROSPINAL FLUID
CHELATING AGENTS
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DISEASES
DRUGS
DTPA
ELECTRON CAPTURE RADIOISOTOPES
FLUID FLOW
HEMIC DISEASES
IMMUNE SYSTEM DISEASES
INDIUM 111
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEUKEMIA
LYMPHOMAS
MATERIALS
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
PATIENTS
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES