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Title: New radionuclide agents for cardiac imaging: Description and application

Journal Article · · Cardiology Clinics; (USA)
OSTI ID:5410554
; ;  [1]
  1. Univ. of Texas Southwestern Medical Center, Dallas (USA)

The introduction of three new radiopharmaceuticals into clinical research and practice has broadened the potential applications and scope of nuclear cardiology examinations. Technetium-99m labeled isonitrile perfusion agents have excellent imaging characteristics allowing the accurate identification of coronary artery disease. Simultaneous assessments of ventricular function are possible with these agents. Iodine-123 phenylpentadecanoic acid myocardial scintigraphy permits assessments of myocardial perfusion and fatty acid metabolism, and permits investigations of myocardial metabolism with conventional imaging equipment. Iodine-123 meta-iodobenzyl-guanidine serves as an indicator of the functional integrity of the sympathetic nervous system and permits evaluations of the effects of various disease states on catecholamine handling by the heart. 58 references.

OSTI ID:
5410554
Journal Information:
Cardiology Clinics; (USA), Vol. 7:3; ISSN 0733-8651
Country of Publication:
United States
Language:
English