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Clinical experiences with intraoperative radiotherapy of locally advanced cancers. [Demonstration of high cure rate and no side effects]

Journal Article · · Cancer; (United States)
OSTI ID:5408264
; ; ; ; ;
Clinical results of intraoperative radiotherapy in neoplasms of the stomach, colon, pancreas, biliary tract, bladder, prostate, lung, mediastinum and brain, and soft-tissue sarcomas are reported. After resectable lesions were removed at surgery, residual cancer nests were sterilized by irradiation before surgical closure. Since the lesion can be exposed directly to radiation and sensitive normal structures are positioned outside the treatment volume, a cancerocidal dose can be safely and precisely delivered to the cancer without affecting normal structure. The great advantage of the intraoperative electron beam therapy lies in the treatment of radioresistant tumors and lesions located near radiosensitive organs. Several patients with unresectable tumors were treated by the intraoperative technique and are alive after more than 5 years.
Research Organization:
Kyoto Univ., Japan
OSTI ID:
5408264
Journal Information:
Cancer; (United States), Journal Name: Cancer; (United States) Vol. 45:1; ISSN CANCA
Country of Publication:
United States
Language:
English

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Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACUTE EXPOSURE
ACUTE IRRADIATION
BILIARY TRACT
BLADDER
BODY
BODY AREAS
BRAIN
CENTRAL NERVOUS SYSTEM
CHEST
DATA
DATA FORMS
DIGESTIVE SYSTEM
DISEASES
ELECTRONS
ELEMENTARY PARTICLES
ENDOCRINE GLANDS
EXPERIMENTAL DATA
FERMIONS
GASTROINTESTINAL TRACT
GLANDS
INFORMATION
INTESTINES
IRRADIATION
ISOLATED VALUES
LARGE INTESTINE
LEPTONS
LOCAL IRRADIATION
LUNGS
MALE GENITALS
MEDIASTINUM
MEDICINE
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
NUMERICAL DATA
ORGANS
PANCREAS
PATIENTS
PROSTATE
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
SIDE EFFECTS
STOMACH
SURGERY
THERAPY
URINARY TRACT