Cadmium toxicity in the free-living nematode, Caenorhabditis elegans

Journal Article · Mon Oct 01 04:00:00 EDT 1979 · Environ. Res.; (United States)

DOI:https://doi.org/10.1016/0013-9351(79)90096-3· OSTI ID:5407161

Popham, J D; Webster, J M

The effect of cadmium on the fecundity, growth, and fine structure of the free-living nematode Caenorhabditis elegans was studied. High concentrations of cadmium significantly decreased the fecundity and growth of these organisms. Electron microscopy showed that cadmium modifies the structure of the mitochondria in the esophagus and intestine, causes the formation of inclusion bodies in the nucleus of esophageal cells, and alters the morphology of cytosomes in the intestinal cells. The results suggest that the decreased fecundity and growth of cadmium-exposed C. elegans may be due to cadmium interfering with nutrient uptake or assimilation or both.

• Research Organization: Simon Fraser Univ., Burnaby, British Columbia
• OSTI ID: 5407161
• Journal Information: Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 20:1; ISSN ENVRA
• Country of Publication: United States
• Language: English

Related Subjects

551000 -- Physiological Systems
560304* -- Chemicals Metabolism & Toxicology-- Invertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL GROWTH
ANIMALS
BIOLOGICAL EFFECTS
CADMIUM
CELL CONSTITUENTS
DATA
DATA FORMS
DIGESTIVE SYSTEM
ELEMENTS
EXPERIMENTAL DATA
FERTILITY
GASTROINTESTINAL TRACT
GROWTH
INFORMATION
INVERTEBRATES
ISOLATED VALUES
METALS
MITOCHONDRIA
MORPHOLOGICAL CHANGES
MORPHOLOGY
NEMATODES
NUMERICAL DATA
NUTRITIONAL DEFICIENCY
ORGANOIDS
QUANTITY RATIO
TIME DEPENDENCE
TOLERANCE
TOXICITY
ULTRASTRUCTURAL CHANGES