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Toxicity of selenium to developing Xenopus laevis embryos

Journal Article · · J. Toxicol. Environ. Health; (United States)

Se in the form of sodium selenite is toxic to Xenopus laevis embryos and tadpoles continuously exposed to concentrations above 1 ppM. Concentrations of 2 ppM and above result in severe developmental abnormalities and increased mortality. Uptake and loss of radioactive Se from water are rapid, but depuration is not complete, indicating that some Se can remain bound by the organism. The facts that Se is toxic at low levels to Xenopus embryos and tadpoles, can cause developmental abnormalities, and accumulates in tissues suggest that increased release of Se compounds into the environmental poses a potential threat to aquatic organisms.

Research Organization:
Oak Ridge National Lab., TN
OSTI ID:
5406867
Journal Information:
J. Toxicol. Environ. Health; (United States), Journal Name: J. Toxicol. Environ. Health; (United States) Vol. 5:4; ISSN JTEHD
Country of Publication:
United States
Language:
English

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