Information profiles on potential occupational hazards: Chlorophenols. Draft report (Second)

Technical Report · Sun Mar 01 04:00:00 EST 1981

OSTI ID:5400007

Information profiles are presented on the following compounds: 2-chlorophenol, 3-chlorophenol, 4-chlorophenol, 2,4-dichlorophenol, 2,5-dichlorophenol, 2,6-dichlorophenol, 2,3,6-trichlorophenol, 2,4,5-trichlorophenol, 2,4,6-trichlorophenol. Studies indicate that, administered in acute lethal doses, the chlorophenols produce excitation and increased respiration followed by motor weakness, hypotonia, convulsions, coma, and death. All chlorophenols are well absorbed dermally, and toxic to skin and eyes. Workers exposed to 4-chlorophenol have demonstrated signs of functional disorders of the central and peripheral nervous systems and mucous membrane structure. Testing in mice has produced increased incidences of hepatocellular carcinomas, adenomas, hepatomas, and reticulum cell sarcomas.

• Research Organization: Syracuse Research Corp., NY (USA). Center for Chemical Hazard Assessment
• OSTI ID: 5400007
• Report Number(s): PB-89-216220/XAB; SRC-TR--81-532
• Country of Publication: United States
• Language: English

Related Subjects

550900 -- Pathology
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
BIOLOGICAL EFFECTS
CHEMICAL PROPERTIES
CHLORINATED AROMATIC HYDROCARBONS
CONTROL EQUIPMENT
DOSES
EQUIPMENT
HALOGENATED AROMATIC HYDROCARBONS
HAZARDS
HEALTH HAZARDS
INDUSTRIAL MEDICINE
LETHAL DOSES
MATERIALS
MEDICINE
OCCUPATIONAL EXPOSURE
OCCUPATIONAL SAFETY
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
PRODUCTION
SAFETY
TOXIC MATERIALS
TOXICITY