Microwave-induced temperature, corticosterone, and thryotropin interrelationships

Journal Article · Thu Jan 01 04:00:00 EST 1981 · J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States)

OSTI ID:5399867

Lu, S T; Lebda, N; Pettit, S; Michaelson, S M

To delineate acute endocrine responses to microwave energy absorption, 142 unanesthetized male Long-Evans rats acclimated to experimental procedures were subjected to far-field 2.45-GHz microwave exposure for 1 h at 1-70 mW/cm/sup 2/, 4 h at 0.1-40 mw/cm/sup 2/, or sham exposure. Controls were sham exposed in a sham-exposure chamber beginning at 030 h and killed at 1230, 1330, 1530, and 1930 h. Microwave-exposed rats were equilibrated in an anechoic chamber for 3 h prior to the start of exposure. Microwave exposure was initiated at 1130 h. Exposed rats were killed at 1230 and 1530 h. Colonic temperature (T/sub col/) was measured and serum obtained for thyrotropin (TSH) and corticosterone (CS) determination immediately after exposure. Inverse relations of TSH to power density (PD) or R/sub col/ were noted in the microwave-exposed rats while CS increased with PD or T/sub col/. Similar relations of TSH and CS to T/sub col/ were also noted among ''shams.'' The increase of T/sub col/ by microwave exposure was dependent on PD but independent of an exposure duration greater than 1 h. The serum CS level increasd with PD but the effect decreased with duration of exposure. ''Low intensity'' 4-h microwave exposure inhibited normal circadian elevation of adrenocortical function in rats if the exposure was coincident with diurnal CS elevation.Inhibition of TSH became more pronounced with duration of exposure. Differences in the endocrine-body temperature relationships between sham- and microwave-exposed rats were also noted. It was concluded that endocrine control was dissociated from body temperature in the microwave-exposed rats. The endocrine control in microwave-exposed rats is different from shams.

• Research Organization: Univ. of Rochester, NY
• DOE Contract Number: AC02-76EV03490
• OSTI ID: 5399867
• Journal Information: J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States), Journal Name: J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States) Vol. 50:2; ISSN JARPD
• Country of Publication: United States
• Language: English

Related Subjects

551000 -- Physiological Systems
560400* -- Other Environmental Pollutant Effects
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL HORMONES
ANIMALS
BIOLOGICAL EFFECTS
BODY
CONTROL
CORTICOSTEROIDS
CORTICOSTERONE
DAILY VARIATIONS
ELECTROMAGNETIC RADIATION
ENDOCRINE GLANDS
GLANDS
GLUCOCORTICOIDS
HORMONES
HYDROXY COMPOUNDS
KETONES
MAMMALS
MICROWAVE RADIATION
ORGANIC COMPOUNDS
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
PREGNANES
RADIATIONS
RATS
RODENTS
SENSITIVITY
STEROID HORMONES
STEROIDS
TEMPERATURE CONTROL
THERMOREGULATION
TSH
VARIATIONS
VERTEBRATES