/sup 201/Tl perfusion study of ''ischemic'' ulcers of the leg: prognostic ability compared with Doppler ultrasound
Journal Article
·
· Radiology; (United States)
OSTI ID:5393870
- Univ. of Southern California, Los Angeles
Thallium 201 perfusion analysis was compared with Doppler ultrasound as a means of determining the healing potential of an ischemic ulcer of the leg in 27 patients. The degree of hyperemia was determined by comparative point counting of the /sup 201/Tl distribution in and about the ulcer. Using established Doppler criteria and a hyperemia ratio greater than 1.5:1, ultrasound alone correctly predicted healing in 15 out of 23 cases and /sup 201/Tl in 20 out of 23. Ultrasound correctly predicted non-healing in 3 out of 6 cases, compared with 5 out of 6 for /sup 201/Tl. The positive predictive value of the /sup 201/Tl study was 63%, versus 27% for ultrasound, and the negative predictive value was 95% for /sup 201/Tl and 83% for ultrasound. The accuracy of /sup 201/Tl and ultrasound was 86% and 62%, respectively. This limited study suggests that /sup 201/Tl perfusion scanning is a useful noninvasive test of ulcer healing potential and may be more sensitive than Doppler ultrasound.
- OSTI ID:
- 5393870
- Journal Information:
- Radiology; (United States), Journal Name: Radiology; (United States) Vol. 143:1; ISSN RADLA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BODY
BODY AREAS
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DETECTION
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
FORECASTING
GAMMA DETECTION
HEAVY NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LEGS
LIMBS
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
RADIATION DETECTION
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOPHARMACEUTICALS
RECOVERY
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
ULTRASONOGRAPHY
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BODY
BODY AREAS
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DETECTION
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
FORECASTING
GAMMA DETECTION
HEAVY NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LEGS
LIMBS
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
RADIATION DETECTION
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOPHARMACEUTICALS
RECOVERY
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
ULTRASONOGRAPHY