Retention of selenium (Se) from vitamin/mineral (V/M) premix and infant formulas

Conference · Mon Mar 11 00:00:00 EST 1991 · FASEB Journal (Federation of American Societies for Experimental Biology); (United States)

OSTI ID:5372071

Mason, A C; Borschel, M W ^[1]

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1. Purdue Univ., West Lafayette, IN (United States) Ross Lab., Columbus, OH (United States)

Selenate (ATE) and selenite (ITE) represent possible sources of Se for fortification of formula. This study assessed the stability and retention of ATE and ITE from V/M premix and soy- and casein-based formulas after 3 mo of storage. Sodium {sup 75}ATE or {sup 75}ITE was incorporated into premix, added to a torula yeast protein-based diet (TYD), and fed to weanling, male, Sprague Dawley rats as a test meal at 3 time: 0 and after 1 and 3 mo storage at room temperature. A premix/{sup 75}Se solution was also added to formula mixes. Complete formulas were processed and gavage fed to rats at 3 times: 0 and after 1 and 3 mo. Control rats were fed test meals of sodium {sup 75}ATE or {sup 75}ITE TYD. Whole-body retention of {sup 75}Se was determined for 10 d post-dose. Retention of ATE and TIE from all diets significantly decreased after 3 mo of storage; however, all rats retained {ge}42% of {sup 75}Se at 10-d post-dose. ATE was equally stable in premix and formula, whereas ITE was more stable in premix than in formula over 3 mo. Independent of storage time, apparent absorption and retention of {sup 75}Se was significantly greater in rats fed ATE compared to ITE.

• OSTI ID: 5372071
• Report Number(s): CONF-9104107-; CODEN: FAJOE
• Journal Information: FASEB Journal (Federation of American Societies for Experimental Biology); (United States), Vol. 5:4; Conference: 75. annual meeting of the Federation of American Societies for Experimental Biology (FASEB), Atlanta, GA (United States), 21-25 Apr 1991; ISSN 0892-6638
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
SELENIUM
METABOLISM
DIET
MILK
RATS
RETENTION
SELENIUM 75
STABILITY
TRACER TECHNIQUES
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY FLUIDS
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
FOOD
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MATERIALS
NUCLEI
RADIOISOTOPES
RODENTS
SELENIUM ISOTOPES
SEMIMETALS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology