Comparative study of two preoperative radiation regimens with cystectomy for bladder cancer

Conference · Thu Sep 01 04:00:00 EDT 1977 · Cancer; (United States)

OSTI ID:5370485

Whitmore, Jr, W F; Batata, M A; Hilaris, B S; Reddy, G N; Unal, A; Ghoneim, M A; Grabstald, H; Chu, F

This report surveys the results of two programs of preoperative irradiation with radical cystectomy for bladder cancer in 205 patients. Irradiating the true pelvis to 4000 rads in 4 weeks with radical cystectomy after 6 weeks was implemented in 119 patients (Group 1) from 1959 to 1965; 2000 rads given in 1 week to the true pelvis and radical cystectomy within the following week was implemented in 86 patients (Group 2) from 1966 to 1970. Determinate survival without evidence of recurrence at 5 years was 43% in Group 1 and 42% in Group 2. Mortality with recurrence of bladder cancer in 5 or more years was 44% in Group 1 and 42% in Group 2. Pelvic complications occurred in 13% of Group 1 and 9% of Group 2.

• Research Organization: Memorial Sloan-Kettering Cancer Center, New York
• OSTI ID: 5370485
• Conference Information: Journal Name: Cancer; (United States) Journal Volume: 40:3
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BLADDER
BODY
BODY AREAS
DISEASES
DOSES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PELVIS
RADIATION DOSES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURGERY
SURVIVAL TIME
THERAPY
URINARY TRACT