Plasma corticosterone concentrations in turkeys inoculated with Pasteurella multocida and maintained at high and low environmental temperatures

Journal Article · Tue Jan 01 04:00:00 EST 1980 · Avian Dis.; (United States)

DOI:https://doi.org/10.2307/1589960· OSTI ID:5364610

Simensen, E; Olson, L D; Ryan, M P; Vanjonack, W J; Johnson, H D

Radioimmunoassay was used to determine plasma corticosterone concentration (PCC) in turkeys inoculated with Pasteurella multocida via either the palatine air spaces or the drinking water and maintained at high (33.4-37.4 C), low (2.6-5.3 C) and moderate )19.8-22.4 C) temperatures in temperature-controlled chambers. In uninoculated turkeys maintained at high temperatures, the PCC was generally lower than in turkeys maintained at moderate temperatures, whereas the opposite occurred in turkeys maintained at low temperatures. After inoculation with P. multocida, all groups of inoculated turkeys showed an increase in the average PCC, which attained a level in some turkeys of over 40 ng/ml, in relation to the average in the uninoculated turkeys, which ranged from 1.8 to 27.3 ng/ml. This increase was proportional to the severity of the infection that developed. The PCC was found to be a sensitive indicator of an incubating infection of P. multocida, since it was markedly increased in turkeys that were bled one day before the onset of depression. In turkeys that were inoculated via the palatine air spaces and maintained at 20 C, the PCC on the day of inoculation was significantly (P less than 0.05) lower in the turkeys that later died than in those that survived. Generally, the PCC was higher in the turkeys that either died between 5 and 10 days after inoculation or were depressed aa the end of the experiment on day 10, relative to the turkeys that were alert at the end of the experiment.

• OSTI ID: 5364610
• Journal Information: Avian Dis.; (United States), Journal Name: Avian Dis.; (United States) Vol. 24:4; ISSN AVDIA
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
ADRENAL HORMONES
ANIMALS
BACTERIAL DISEASES
BIOCHEMICAL REACTION KINETICS
BIRDS
CHOLERA
CORTICOSTEROIDS
CORTICOSTERONE
DISEASES
EXPOSURE CHAMBERS
FOWL
GLUCOCORTICOIDS
HORMONES
HYDROXY COMPOUNDS
INFECTIOUS DISEASES
INOCULATION
ISOTOPE APPLICATIONS
KETONES
KINETICS
ORGANIC COMPOUNDS
PATHOGENESIS
PATHOLOGY
PREGNANES
RADIOASSAY
RADIOIMMUNOASSAY
REACTION KINETICS
STEROID HORMONES
STEROIDS
TEMPERATURE EFFECTS
TRACER TECHNIQUES
VERTEBRATES