Prior irradiation and the development of coexistent differentiated thyroid cancer and hyperparathyroidism

Journal Article · Mon Mar 01 04:00:00 EST 1982 · Cancer (Philadelphia); (United States)

DOI:https://doi.org/10.1002/1097-0142(19820301)49:5<874::AID-CNCR2820490509>3.0.CO;2-D· OSTI ID:5363157

Prinz, R A; Barbato, A L; Braithwaite, S S; Brooks, M H; Lawrence, A M; Paloyan, E

Twelve patients with coexistent well-differentiated thyroid carcinoma and primary hyperparathyoidism were studied to determine the frequency of previous radiation exposure. Eight were found to have received prior irradiation. External radiation was administered to the head and neck region for benign conditions such as tonsillar enlargement, acne, scrofula, and thyroid enlargement. One patient received 131I therapy for carcinoma of the thyroid. The observation that 67% of the patients in this series had previous radiation to the head and neck strongly implicates radiation exposure in the development of coexistent well-differentiated thyroid carcinoma and hyperparathyroidism.

• Research Organization: Edward Hines, Jr. Medical Center, Hines, Illinois
• OSTI ID: 5363157
• Journal Information: Cancer (Philadelphia); (United States), Journal Name: Cancer (Philadelphia); (United States) Vol. 49:5; ISSN CANCA
• Country of Publication: United States
• Language: English

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