Genetic diversity and linkage disequilibrium in Drosophila melanogaster with different rates of development

Journal Article · Sun Nov 01 04:00:00 EST 1987 · Genetics; (United States)

OSTI ID:5355947

Marinkovic, D; Tucic, N; Moya, A; Ayala, F J

The authors examined eight enzyme polymorphisms in groups of Drosophila melanogaster flies with fast, intermediate and slow development. The allelic frequencies are similar in all three developmental classes, but the distribution of the genotypes among the class is significantly heterogeneous for the three loci on the second chromosome. When the total sample of 300 individuals is examined, significant gametic disequilibrium appears in 3 out of 13 pairs of genes located on the same chromosome and in 4 out of 15 pairs of genes located on different chromosomes. This 25% incidence of disequilibrium between pairs of genes is larger than previously observed in other natural populations (but similar to the incidence observed in laboratory populations). The greater frequency of significant gametic disequilibrium in our study is probably due to the large number of genomes sampled. Some models specifically predict that individuals with faster rates of development (i.e., greater fitness) should be more heterozygous (and exhibit more linkage disequilibrium) than individuals with slower development. This hypothesis is not supported by our results.

• Research Organization: Univ. of Belgrade, Yugoslavia
• OSTI ID: 5355947
• Journal Information: Genetics; (United States), Journal Name: Genetics; (United States) Vol. 117:3; ISSN GENTA
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
59 BASIC BIOLOGICAL SCIENCES
ACID PHOSPHATASE
ALCOHOL DEHYDROGENASE
ANIMALS
ARTHROPODS
BIOLOGICAL VARIABILITY
DIPTERA
DROSOPHILA
ELECTROPHORESIS
ENZYMES
ESTERASES
FLIES
FRUIT FLIES
GAMETES
GENES
GENETIC VARIABILITY
GERM CELLS
HEMIACETAL DEHYDROGENASES
HYDROLASES
INSECTS
INVERTEBRATES
MALES
ONTOGENESIS
OXIDOREDUCTASES
PHOSPHATASES
PHOSPHORUS-GROUP TRANSFERASES
PHOSPHOTRANSFERASES
SUPEROXIDE DISMUTASE
TRANSFERASES