Structure of the main oligomannoside chains of the hemagglutinin of the influenza virus A/Leningrad/385/80/ (H3N2)

Journal Article · Mon Sep 01 00:00:00 EDT 1986 · Sov. J. Bioorg. Chem. (Engl. Transl.); (United States)

OSTI ID:5349301

Arbatskii, N P; Shashkov, A S; Zheltova, A O; Yurtov, D V; Derevitskaya, V A; Kochetkov, N K

The structure of the four main oligomannoside carbohydrate chains from the hemagglutinin of the influenza virus A/Leningrad/385/80 (H3N2) have been established with the aid of /sup 1/H NMR spectroscopy. On the basis of the results obtained, the hypothesis has been put forward that the splitting out by ..cap alpha..-mannosidase I of four ..cap alpha..-1- ..-->.. 2-bound mannose residues in the transformation of the oligomannoside chain into a complex one is the limiting and selective stage of the processing of the carbohydrate chains in the biosynthesis of glycoproteins.

• Research Organization: N. D. Zelinskii Institute of Organic Chemistry, Moscow (USSR)
• OSTI ID: 5349301
• Journal Information: Sov. J. Bioorg. Chem. (Engl. Transl.); (United States), Vol. 11:11; Other Information: Translated from Bioorganicheskaya Khim.; 11: No. 11, 1556-1561(Nov 1985)
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
HEMAGGLUTININS
DEUTERATION
MOLECULAR STRUCTURE
NMR SPECTRA
RADIOENZYMATIC ASSAY
OLIGOSACCHARIDES
ANTIGENS
BIOCHEMISTRY
BIOSYNTHESIS
CHEMICAL SHIFT
COUPLING CONSTANTS
ENZYME ACTIVITY
GLUCOPROTEINS
HEAVY WATER
HYDROGEN 1
INFLUENZA VIRUSES
J-J COUPLING
MANNOSE
TRANSFERASES
AGGLUTININS
ALDEHYDES
ANTIBODIES
CARBOHYDRATES
CHEMICAL REACTIONS
CHEMISTRY
COUPLING
ENZYMES
HEXOSES
HYDROGEN COMPOUNDS
HYDROGEN ISOTOPES
INTERMEDIATE COUPLING
ISOTOPES
LIGHT NUCLEI
MICROORGANISMS
MONOSACCHARIDES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
PARASITES
PROTEINS
SACCHARIDES
SPECTRA
STABLE ISOTOPES
SYNTHESIS
VIRUSES
WATER
550201* - Biochemistry- Tracer Techniques