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Photochemistry of vinyl halides. Formation of benzofurans by photolysis of. beta. -(o-methoxyphenyl)vinyl bromides

Journal Article · · J. Org. Chem.; (United States)
DOI:https://doi.org/10.1021/jo00339a012· OSTI ID:5313902

Photolysis of ..beta..,..beta..-bix(o-methoxyphenyl)-substituted vinyl bromides gave benzofuran derivatives which are derived from an intramolecular nucleophilic attack of the methoxyl group on an intermediate vinyl cation. With ..cap alpha..-aryl-substituted vinyl bromides, only one type of benzofuran derivative was detected. However, when the ..cap alpha.. substituent was a hydrogen or a methyl group, two isomeric benzofurans were formed, one via the unrearranged vinyl cation and the other via an (o-methoxyphenyl)-rearranged vinyl cation. Irradiation of ..cap alpha..-methyl-..beta..,..beta..-bis-(o-methoxyphenyl)vinyl bromide in nucleophilic solvent, i.e., methanol, did not result in solvent-incorporated products. In the photolysis of ..beta..-(o-methoxyphenyl)-substituted vinyl bromides a selectivity-reactivity relationship between the cyclization and the rearrangement of the initially formed vinyl cation was observed.

Research Organization:
Kyushu Univ., Fukuoka, Japan
OSTI ID:
5313902
Journal Information:
J. Org. Chem.; (United States), Journal Name: J. Org. Chem.; (United States) Vol. 46:26; ISSN JOCEA
Country of Publication:
United States
Language:
English