Gene structure and expression

Book · Mon Jan 01 04:00:00 EST 1990

OSTI ID:5313671

Hawkins, J ^[1]

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1. London Univ. (United Kingdom)

This book describes the structure of genes in molecular terms and summarizes present knowledge about how their activity is regulated. It covers a range of topics, including a review of the structure and replication of DNA, transcription and translation, prokaryotic and eukaryotic gene organization and expression, retroviruses and oncogenes. The book also includes a chapter on the methodology of DNA manipulation including sections on site-directed mutagenesis, the polymerase chain reaction, reporter genes and restriction fragment length polymorphisms. The hemoglobin gene system and the genetics of the proteins of the immune system are presented in the latter half of the book to show the structure and expression of the most well-studied systems in higher eukaryotes. The final chapter reviews the differences between prokaryotic and the eukaryotic genomes.

• OSTI ID: 5313671
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
59 BASIC BIOLOGICAL SCIENCES
CARBOXYLIC ACIDS
DNA
DNA REPLICATION
ENZYMES
GENE REGULATION
GENES
GLOBINS
HEMOGLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
IMMUNOLOGY
KARYOTYPE
MICROORGANISMS
MOLECULAR BIOLOGY
MOLECULAR STRUCTURE
MUTAGENESIS
NUCLEIC ACID REPLICATION
NUCLEIC ACIDS
NUCLEOTIDYLTRANSFERASES
ONCOGENES
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PARASITES
PHOSPHORUS-GROUP TRANSFERASES
PIGMENTS
POLYMERASES
PORPHYRINS
PROTEINS
TRANSCRIPTION
TRANSFERASES
VIRUSES