Fissural thickening and exposure to asbestos: occurrence, determinants, and functional impact

Journal Article · Tue Jan 01 04:00:00 EST 1991 · American Journal of Industrial Medicine; (United States)

DOI:https://doi.org/10.1002/ajim.4700200610· OSTI ID:5308706

Zejda, J; Ernst, P ^[1]

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1. Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, (Canada)

The occurrence and determinants of thickened interlobar fissures were assessed in 147 insulators, in order to test the hypothesis that radiographic abnormalities in minor (FMN) and/or major (FMJ) interlobar fissures are associated with restrictive respiratory impairment, which may reflect early parenchymal lung fibrosis. According to the diagnostic criteria developed, definite interlobar thickening was found in 33 (FMN) and in 73 (FMJ) men, and was frequently associated with the presence of classical asbestos pleural disease, though not parenchymal abnormality. Multivariate analyses did not demonstrate any association between either FMN or FMJ and lung function. Such an association, however, was found in the case of the usual asbestos-related pleural change. These findings suggest that fissural thickening seen on chest radiography represents a component of asbestos pleural disease and not asbestosis.

• OSTI ID: 5308706
• Journal Information: American Journal of Industrial Medicine; (United States), Journal Name: American Journal of Industrial Medicine; (United States) Vol. 20:6; ISSN 0271-3586; ISSN AJIMD
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ASBESTOS
BODY
DISEASES
FIBROSIS
HAZARDS
HEALTH HAZARDS
LUNGS
MATHEMATICS
MULTIVARIATE ANALYSIS
OCCUPATIONAL EXPOSURE
ORGANS
PATHOLOGICAL CHANGES
PERSONNEL
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
STATISTICS