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Radiation-induced recurrent intestinal pseudo-obstruction

Journal Article · · Am. J. Gastroenterol.; (United States)
OSTI ID:5308254
;
The syndrome of intestinal pseudo-obstruction is a complex of signs and symptoms of intestinal obstruction without evidence of mechanical obstruction of the intestinal lumen. A patient with radiation-induced intestinal pseudoobstruction is described. The patient is a 74-year old woman with a history of chronic diarrhea, recurrent episodes of crampy abdominal pain, nausea and vomiting since receiving a 13,000 rad radiation dose to the pelvis in 1954. She has been hospitalized on many occasions for symptoms and signs of bowel obstruction. Upper gastrointestinal contrast roentgenograms with small bowel follow-through done during these episodes revealed multiple dilated loops of small bowel with no obstructing lesion. Barium enemas revealed no obstructing lesion. Each episode resolved with conservative therapy. Other secondary causes for intestinal pseudo-obstruction were ruled out in our patient. She gave no history of familial gastrointestinal disorders. Although postirradiation motility abnormalities have been demonstrated experimentally this is the first report of radiation induced intestinal pseudo-obstruction.
OSTI ID:
5308254
Journal Information:
Am. J. Gastroenterol.; (United States), Journal Name: Am. J. Gastroenterol.; (United States) Vol. 75:6; ISSN AJGAA
Country of Publication:
United States
Language:
English

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Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
550901 -- Pathology-- Tracer Techniques
560151 -- Radiation Effects on Animals-- Man
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DIGESTIVE SYSTEM
DOSES
GASTROINTESTINAL TRACT
INTESTINES
IRRADIATION
LOCAL IRRADIATION
MEDICINE
NAUSEA
NUCLEAR MEDICINE
ORGANS
PAIN
PATHOLOGY
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SMALL INTESTINE
SYMPTOMS
THERAPY
VOMITING