In vivo metabolic activity of hamster suprachiasmatic nuclei: use of anesthesia
Journal Article
·
· Am. J. Physiol.; (United States)
OSTI ID:5298914
In vivo glucose utilization was measured in the suprachiasmatic nuclei (SCN) of Golden hamsters using the /sup 14/C-labeled deoxyglucose technique. A circadian rhythm of SCN metabolic activity could be measured in this species, but only during pentobarbital sodium anesthesia when the surrounding background activity of adjacent hypothalamus was suppressed. Both the SCN's metabolic oscillation and its time-keeping ability are resistant to general anesthesia.
- Research Organization:
- Harvard Medical School, Boston, MA
- OSTI ID:
- 5298914
- Journal Information:
- Am. J. Physiol.; (United States), Vol. 252:2
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
CARBON 14 COMPOUNDS
METABOLISM
HYPOTHALAMUS
AUTORADIOGRAPHY
PHYSIOLOGY
ANESTHESIA
DAILY VARIATIONS
GLUCOSE
HAMSTERS
IN VIVO
ALDEHYDES
ANIMALS
BODY
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
HEXOSES
LABELLED COMPOUNDS
MAMMALS
MONOSACCHARIDES
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
RODENTS
SACCHARIDES
VARIATIONS
VERTEBRATES
551001* - Physiological Systems- Tracer Techniques
550601 - Medicine- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
CARBON 14 COMPOUNDS
METABOLISM
HYPOTHALAMUS
AUTORADIOGRAPHY
PHYSIOLOGY
ANESTHESIA
DAILY VARIATIONS
GLUCOSE
HAMSTERS
IN VIVO
ALDEHYDES
ANIMALS
BODY
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
HEXOSES
LABELLED COMPOUNDS
MAMMALS
MONOSACCHARIDES
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
RODENTS
SACCHARIDES
VARIATIONS
VERTEBRATES
551001* - Physiological Systems- Tracer Techniques
550601 - Medicine- Unsealed Radionuclides in Diagnostics