In vivo metabolic activity of hamster suprachiasmatic nuclei: use of anesthesia
Journal Article
·
· Am. J. Physiol.; (United States)
OSTI ID:5298914
In vivo glucose utilization was measured in the suprachiasmatic nuclei (SCN) of Golden hamsters using the /sup 14/C-labeled deoxyglucose technique. A circadian rhythm of SCN metabolic activity could be measured in this species, but only during pentobarbital sodium anesthesia when the surrounding background activity of adjacent hypothalamus was suppressed. Both the SCN's metabolic oscillation and its time-keeping ability are resistant to general anesthesia.
- Research Organization:
- Harvard Medical School, Boston, MA
- OSTI ID:
- 5298914
- Journal Information:
- Am. J. Physiol.; (United States), Journal Name: Am. J. Physiol.; (United States) Vol. 252:2; ISSN AJPHA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ALDEHYDES
ANESTHESIA
ANIMALS
AUTORADIOGRAPHY
BODY
BRAIN
CARBOHYDRATES
CARBON 14 COMPOUNDS
CENTRAL NERVOUS SYSTEM
DAILY VARIATIONS
GLUCOSE
HAMSTERS
HEXOSES
HYPOTHALAMUS
IN VIVO
LABELLED COMPOUNDS
MAMMALS
METABOLISM
MONOSACCHARIDES
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
PHYSIOLOGY
RODENTS
SACCHARIDES
VARIATIONS
VERTEBRATES
551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ALDEHYDES
ANESTHESIA
ANIMALS
AUTORADIOGRAPHY
BODY
BRAIN
CARBOHYDRATES
CARBON 14 COMPOUNDS
CENTRAL NERVOUS SYSTEM
DAILY VARIATIONS
GLUCOSE
HAMSTERS
HEXOSES
HYPOTHALAMUS
IN VIVO
LABELLED COMPOUNDS
MAMMALS
METABOLISM
MONOSACCHARIDES
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
PHYSIOLOGY
RODENTS
SACCHARIDES
VARIATIONS
VERTEBRATES