Evidence for alterations in luteinizing hormone secreted in rhesus monkeys with normal and inadequate luteal phases using radioreceptor and radioimmunoassay
Journal Article
·
· Endocrinology; (United States)
A radioreceptor assay (RRA) using porcine granulosa cells and (/sup 125/I)hCG was developed and validated for the measurement of LH or CG. The RRA was used in conjunction with a heterologous RIA employing antiserum against ovine LH and (/sup 125/I)ovine LH (RIA) to measure serum LH in the rhesus monkey throughout the menstrual cycle. Discrepancies were found in the measurement of serum LH using RRA and RIA. Measurements of serum LH using RIA were consistently higher than the measurements of serum LH using RRA in serum from adult intact female and male monkeys and hypophysectomized, ovariectomized, and pregnant monkeys.
- Research Organization:
- Univ. of Maryland School of Medicine, Baltimore
- OSTI ID:
- 5292366
- Journal Information:
- Endocrinology; (United States), Journal Name: Endocrinology; (United States) Vol. 104:5; ISSN ENDOA
- Country of Publication:
- United States
- Language:
- English
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· J. Clin. Endocrinol. Metab., v. 41, no. 3, pp. 581-589
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Related Subjects
550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
BETA DECAY RADIOISOTOPES
DATA
DATA FORMS
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
ESTROUS CYCLE
EXPERIMENTAL DATA
GONADOTROPINS
HORMONES
INFORMATION
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOLATED VALUES
ISOTOPE APPLICATIONS
ISOTOPES
LH
MAMMALS
MONKEYS
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
PEPTIDE HORMONES
PITUITARY HORMONES
PRIMATES
RADIOASSAY
RADIOIMMUNOASSAY
RADIOISOTOPES
TRACER TECHNIQUES
VARIATIONS
VERTEBRATES
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
BETA DECAY RADIOISOTOPES
DATA
DATA FORMS
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
ESTROUS CYCLE
EXPERIMENTAL DATA
GONADOTROPINS
HORMONES
INFORMATION
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOLATED VALUES
ISOTOPE APPLICATIONS
ISOTOPES
LH
MAMMALS
MONKEYS
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
PEPTIDE HORMONES
PITUITARY HORMONES
PRIMATES
RADIOASSAY
RADIOIMMUNOASSAY
RADIOISOTOPES
TRACER TECHNIQUES
VARIATIONS
VERTEBRATES