Cancer in children of parents exposed to hydrocarbon-related industries and occupations

Journal Article · Sat Mar 01 04:00:00 EST 1980 · Am. J. Epidemiol.; (United States)

OSTI ID:5287447

Zack, M; Cannon, S; Loyd, D; Heath, Jr, C W; Falletta, J M; Jones, B; Housworth, J; Crowley, S

Recent animal and human studies suggest that prenatal exposure to carcinogens may increase the risk of childhood malignancy. The Texas Childhood Cancer Study (1976-1977) was designed to test the hypothesis that parental exposure to hydrocarbon-related occupations or industries increases this risk. The study subjects, parents of children with and without cancer, were questioned about their job histories. Parents of 296 children with cancer were not exposed to hydrocarbon-related occupations or industries more often than the uncles and aunts of these children, the parents of neighborhood children, or the parents of 283 children without cancer. During the year before birth, odds ratios for fathers of children seen at a hematology clinic with cancer relative to the uncles of these children (0.93), the fathers of neighborhood children (1.33), and the fathers of children seen at the clinic without cancer (0.50) were not statistically significantly different from 1.00 (p > 0.05). This lack of association persisted for the year after birth, the year before diagnosis, and the interval from the year before birth to the year of diagnosis; for different diagnoses; for different ages at diagnosis; and for the industries and occupations of female as well as male parents.

• OSTI ID: 5287447
• Journal Information: Am. J. Epidemiol.; (United States), Journal Name: Am. J. Epidemiol.; (United States) Vol. 111:3; ISSN AJEPA
• Country of Publication: United States
• Language: English

Related Subjects

550900 -- Pathology
552000 -- Public Health
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
ANIMALS
CARCINOGENESIS
CHILDREN
DISEASES
EPIDEMIOLOGY
HAZARDS
HEALTH HAZARDS
HYDROCARBONS
INDUSTRIAL PLANTS
MAMMALS
MAN
NEOPLASMS
ORGANIC COMPOUNDS
PATHOGENESIS
PERSONNEL
PREGNANCY
PRIMATES
PROGENY
RISK ASSESSMENT
VERTEBRATES