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Candidiasis of the liver and spleen in childhood

Journal Article · · Radiology; (United States)
Four children with acute leukemia and surgically documented candidiasis of the liver and/or spleen were examined with a combination of diagnostic imaging modalities including /sup 99/mTc-sulfur colloid and /sup 67/Ga-citrate scintigraphy, gray-scale ultrasound, and body computed tomography (CT). Abnormalities were detected in every individual examined. /sup 99/mTc-sulfur colloid scintigraphy revealed cold areas in the liver or spleen. With /sup 67/Ga scintigraphy, these areas were cold in some individuals and hot in others. Gray-scale ultrasound demonstrated hypoechoic lesions with central areas of increased echogenicity in hepatic involvement, and hypoechoic replacement of the spleen in splenic involvement. CT in one patient revealed low-density areas without contrast enhancement within the hepatic parenchyma and unsuspected renal involvement.
Research Organization:
Division of Nuclear Radiology and Diagnostic Ultrasound, Childrens Hospital of Los Angeles, CA
OSTI ID:
5284716
Journal Information:
Radiology; (United States), Journal Name: Radiology; (United States) Vol. 142:2; ISSN RADLA
Country of Publication:
United States
Language:
English