Acetylcholine content and cholinesterase activity as related to the combined effects of allergen and radiation. [Rats, gamma radiation]

Journal Article · Sat Jan 01 00:00:00 EST 1977 · Radiobiology (USSR) (Engl. Transl.); (United States)

OSTI ID:5275894

Lipshits, R U; Kratinova, M A

Rats were given intraperitoneal injections of antigen and exposed to 200 R of gamma radiation. Acetylcholine content and cholinesterase activity of blood were analyzed every 5 days for 30 days. The interval between sensitization and irradiation determined the direction of changes in allergic reactions. The radiation appreciably attenuated active sensitization of rats. The degree of sensitization was related to changes in cholinergic processes. The data confirmed the assumption that cholinergic systems are involved in the mechanisms of change in allergic reactivity under the influence of radiation. (HLW)

• Research Organization: Khar'kov Medical Inst.
• OSTI ID: 5275894
• Journal Information: Radiobiology (USSR) (Engl. Transl.); (United States), Vol. 17:2; Other Information: Translated from Radiobiologiya; 17: No. 2, 296-299(1977)
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACETYLCHOLINE
BIOLOGICAL RADIATION EFFECTS
ANTIGENS
RADIOSENSITIVITY EFFECTS
CHOLINESTERASE
IMMUNE REACTIONS
ALLERGY
GAMMA RADIATION
METABOLISM
RATS
AMINES
AMMONIUM COMPOUNDS
ANIMALS
BIOLOGICAL EFFECTS
DISEASES
DRUGS
ELECTROMAGNETIC RADIATION
ENZYMES
ESTERASES
ESTERS
HYDROLASES
IONIZING RADIATIONS
MAMMALS
ORGANIC COMPOUNDS
PARASYMPATHOMIMETICS
PATHOLOGICAL CHANGES
QUATERNARY COMPOUNDS
RADIATION EFFECTS
RADIATIONS
RODENTS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals