Influence of field size, treatment modality, commissure involvement and histology in the treatment of early vocal cord cancer with irradiation
One hundred and thirty-seven patients with TNM staged T1 glottic cancer were treated from 1966 to 1980. Patients were treated either with /sup 60/Co teletherapy units or 4 MeV linear accelerators with different daily and weekly fractionation schemes. A recurrent-free survival was attained in 80% of the patients 2 years after primary treatment with radiation therapy. There were 27 local recurrences of which 82% were salvaged with surgery for an overall adjusted survival of 95%. Poorly differentiated tumors and those involving the anterior commissure were more likely to develop a local recurrence. Voice quality remained good to excellent in 79% of patients. Edema and mucositis were the major side effects.
- Research Organization:
- St. Mary's Hospital and Medical Center, San Francisco, CA
- OSTI ID:
- 5269307
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 11:7
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARCINOMAS
RADIOTHERAPY
EDEMA
RADIOINDUCTION
LARYNX
SIDE EFFECTS
COBALT 60
GAMMA RADIATION
HISTOLOGY
LINEAR ACCELERATORS
MEV RANGE 01-10
MUCOUS MEMBRANES
PAIN
ACCELERATORS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
COBALT ISOTOPES
DISEASES
ELECTROMAGNETIC RADIATION
ENERGY RANGE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MEMBRANES
MEV RANGE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
PATHOLOGICAL CHANGES
RADIATIONS
RADIOISOTOPES
RADIOLOGY
RESPIRATORY SYSTEM
SYMPTOMS
THERAPY
YEARS LIVING RADIOISOTOPES
550603* - Medicine- External Radiation in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man