Experimental lead poisoning in horses and Spanish goats

Journal Article · Wed Jan 01 00:00:00 EST 1975 · Southwest. Vet.; (United States)

OSTI ID:5267888

Dollahite, J W; Rowe, L D; Reagor, J C

Lead was administered as an aqueous solution of lead acetate to 3 horses and 9 goats. Horse number 3 survived 2 administrations of 1000 mg Pb/kg. body weight, 170 days apart. Horse number 5 was showing signs of lead poisoning after receiving 100 mg/kg./day for 28 days. This horse died when lead acetate solution was accidently placed in the trachea. Horse number 7 died after receiving 200 mg/kg./day for 9 days. The two ponies that died had liver lead levels of 91 and 206 ppm, renal cortex 225 and 183 ppm, and renal medulla 42 and 75 ppm. Four pregnant Spanish goats aborted and died after receiving from 400 to 3200 mg Pb/kg. body weight. Three non-pregnant goats died from lead intoxication after receiving 400 to 3200 mg/kg. One goat survived and gained weight after receiving 2 doses of 1600 mg/kg. body weight 132 days apart. Animals will abort after ingestion of lead, and the cause of abortion can be diagnosed by analysis of fetal liver for lead. 20 references.

• Research Organization: Texas A and M Univ., College Station
• OSTI ID: 5267888
• Journal Information: Southwest. Vet.; (United States), Vol. 28:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LEAD
TOXICITY
ABORTION
BIOLOGICAL ACCUMULATION
BLOOD
DOSE-RESPONSE RELATIONSHIPS
EXPERIMENTAL DATA
GOATS
HORSES
KIDNEYS
LIVER
MORTALITY
TEXAS
ANIMALS
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
DATA
DIGESTIVE SYSTEM
DOMESTIC ANIMALS
ELEMENTS
FEDERAL REGION VI
GLANDS
INFORMATION
MAMMALS
MATERIALS
METALS
NORTH AMERICA
NUMERICAL DATA
ORGANS
RUMINANTS
USA
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)