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Title: The immunobiology and immunotherapy of ovarian cancer

Journal Article · · Seminars in Oncology; (United States)
OSTI ID:5265259
;  [1]
  1. Fox Chase Cancer Center, Philadelphia, PA (USA)

Small volume residual peritoneal disease in patients undergoing therapy for ovarian carcinoma remains an attractive, but elusive, target for immunobiological therapy. Hypothetical advantages and disadvantages of regional peritoneal therapy are being better defined through increased clinical experience and more sophisticated animal models. Developments in cytokine biology, adoptive cellular therapy, monoclonal antibody conjugation, and molecular biology continue to provide an exciting, and nearly overwhelming, array of reagents for clinical evaluation. Ongoing and anticipated investigational trials should provide intriguing data in years to follow.198 references.

OSTI ID:
5265259
Journal Information:
Seminars in Oncology; (United States), Vol. 18:3; ISSN 0093-7754
Country of Publication:
United States
Language:
English