Asbestos, dental x-rays, tobacco, and alcohol in the epidemiology of laryngeal cancer

Journal Article · Sat Sep 01 04:00:00 EDT 1979 · Cancer; (United States)

OSTI ID:5262507

Hinds, M W; Thomas, D B; O'Reilly, H P

A case-control study of 47 laryngeal cancers in males of three counties of Washington State was conducted. Personal interview was used to obtain information on smoking, alcohol use, exposure to asbestos, and other substances, and x-rays of the head and neck area. Smoking and alcohol consumption were found to increase risk of laryngeal cancer independently, with a clear dose-response relationship. Neither asbestos exposure nor exposure to other substances was found to significantly increase the risk of laryngeal cancer, although the relative risk with asbestos exposure was 1.75. Lifetime history of exposure to dental x-rays on five or more occasions was associated with significantly increased risk of laryngeal cancer among heavy smokers but not among light smokers. The importance of tobacco and alcohol in the epidemiology of laryngeal cancer was re-affirmed, the importance of asbestos exposure was brought into question, and a possible relationship of laryngeal cancer with exposure to dental x-rays among heavy smokers was demonstrated.

• OSTI ID: 5262507
• Journal Information: Cancer; (United States), Journal Name: Cancer; (United States) Vol. 44:3; ISSN CANCA
• Country of Publication: United States
• Language: English

Related Subjects

500200 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
552000 -- Public Health
560151* -- Radiation Effects on Animals-- Man
560306 -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
AEROSOLS
ALCOHOLS
ANIMALS
ASBESTOS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMEDICAL RADIOGRAPHY
CARCINOGENESIS
COLLOIDS
DELAYED RADIATION EFFECTS
DENTISTRY
DIAGNOSTIC TECHNIQUES
DISEASES
DISPERSIONS
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
EPIDEMIOLOGY
ETHANOL
ETIOLOGY
HYDROXY COMPOUNDS
IONIZING RADIATIONS
LARYNX
MALES
MAMMALS
MAN
MEDICINE
MEN
NEOPLASMS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
PATHOGENESIS
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOLOGY
RADIOSENSITIVITY EFFECTS
RESIDUES
RESPIRATORY SYSTEM
SIDE EFFECTS
SMOKES
SOLS
TOBACCO SMOKES
TOXICITY
VERTEBRATES
X RADIATION