Membrane interfaces for sample introduction in capillary zone electrophoresis

Journal Article · Fri May 01 04:00:00 EDT 1992 · Analytical Chemistry (Washington)

DOI:https://doi.org/10.1021/ac00033a006· OSTI ID:526059

Bao, L; Dasgupta, P K ^[1]

---

1. Texas Tech Univ., Lubbock, TX (United States)

Small lengths of narrow-bore tubular membranes can be interposed in the separation capillary in capillary electrophoretic separation systems. These membrane segments can be used as sampling interfaces; a jacket is built outside the membrane, and the sample is introduced by diffusion/permeation through the membrane. Various examples are shown; the determination of gaseous samples through a porous membrane, the determination of ionizable/nonionic solutes by permeation through a silicone rubber membrane, and the separation of low MW constituents in blood plasma by transport through a dialysis membrane. In the first two cases, significant preconcentration is possible, thus permitting attractive detection limits. 23 refs., 10 figs., 2 tabs.

• Sponsoring Organization: USDOE
• DOE Contract Number: FG05-84ER13281
• OSTI ID: 526059
• Journal Information: Analytical Chemistry (Washington), Journal Name: Analytical Chemistry (Washington) Journal Issue: 9 Vol. 64; ISSN ANCHAM; ISSN 0003-2700
• Country of Publication: United States
• Language: English

Related Subjects

44 INSTRUMENTATION
INCLUDING NUCLEAR AND PARTICLE DETECTORS
54 ENVIRONMENTAL SCIENCES
55 BIOLOGY AND MEDICINE
BASIC STUDIES
CAPILLARIES
CAPILLARY FLOW
DETECTION
DIALYSIS
DIFFUSION
EFFICIENCY
ELECTROPHORESIS
FILTERS
INTERFACES
LIMITING VALUES
LIQUID COLUMN CHROMATOGRAPHY
MASS TRANSFER
MEMBRANES
PERFORMANCE
PERMEABILITY
POROSITY
SAMPLE PREPARATION
SEPARATION EQUIPMENT
USES