Alterations in cerebral blood flow in preterm infants with intraventricular hemorrhage

Journal Article · Tue Dec 01 04:00:00 EST 1981 · Pediatrics; (United States)

OSTI ID:5244479

Ment, L R; Ehrenkranz, R A; Lange, R C; Rothstein, P T; Duncan, C C

Xenon-133 inhalation hemispheric cerebral blood flow (HCBF) determinations at one to two days and four to six days postnatally and at 37 weeks postconceptual age have been correlated with computed tomography (CT) scan and autopsy findings in 15 preterm infants weighing less than 1,250 gm at birth. Ten of these infants had germinal matrix hemorrhages (GMH) or intraventricular hemorrhages (IVH). Although HCBF obtained at one to two days showed no mean difference between the GMH/IVH group and the nonhemorrhage infants, hemispheric flow ratios showed significant discrepancies in the GMH/IVH group. In addition, in four of five patients in whom the hemorrhage appeared asymmetric on CT scan, the side of higher flow correlated with the hemorrhage. At four to six days HCBF showed a lower mean value in the GMH/IVH patients than in the nonhemorrhage patients and differences in the interhemispheric ratios in the GMH/IVH group persisted. There were no differences in the mean HCBF values or hemispheric ratios between the two groups of infants at 37 weeks postconceptual age.

• Research Organization: Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut
• OSTI ID: 5244479
• Journal Information: Pediatrics; (United States), Journal Name: Pediatrics; (United States) Vol. 68:6; ISSN PEDIA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
550901 -- Pathology-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
AGE GROUPS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CEREBRUM
CHILDREN
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
EVEN-ODD NUCLEI
HEMORRHAGE
INFANTS
INHALATION
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NERVOUS SYSTEM
NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PATHOLOGY
PATIENTS
PEDIATRICS
RADIOISOTOPES
SYMPTOMS
TOMOGRAPHY
USES
XENON 133
XENON ISOTOPES