CT of acquired cystic kidney disease and renal tumors in long-term dialysis patients

Journal Article · Sun Jan 01 04:00:00 EST 1984 · AJR, Am. J. Roentgenol.; (United States)

DOI:https://doi.org/10.2214/ajr.142.1.125· OSTI ID:5242204

Levine, E; Grantham, J J; Slusher, S L; Greathouse, J L; Krohn, B P

The kidneys of long term dialysis patients frequently demonstrate multiple small acquired cysts and renal cell tumors on pathologic examination. The original kidneys of 30 long-term dialysis patients and six renal transplant patients were evaluated by computed tomography to determine the incidence of these abnormalities. Among dialysis patients, 43.3% had diffuse bilateral cysts, while 16.7% had occasional cysts (fewer than five per kidney), and 40% showed no renal cysts. Seven solid renal tumors were detected in four dialysis patients with renal cysts. Acquired cystic kidney disease tends to result in renal enlargement, is more common in patients who have been maintained on dialysis for prolonged periods, and may lead to spontaneous renal hemorrhage. The six transplant patients showed no evidence of renal cysts, and all had markedly shrunken kidneys. Acquired cystic disease and renal cell tumors in the original kidneys of dialysis patients may be due to biologically active substances that are not cleared effectively by dialysis but that are removed by normally functioning transplant kidneys.

• Research Organization: Univ. of Kansas Coll. of Health Sciences and Hospital, Kansas City
• OSTI ID: 5242204
• Journal Information: AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Vol. 142:1; ISSN AAJRD
• Country of Publication: United States
• Language: English

Related Subjects

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550900 -- Pathology
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIALYSIS
DISEASES
KIDNEYS
NEOPLASMS
ORGANS
PATHOLOGY
PATIENTS
SEPARATION PROCESSES
SIDE EFFECTS
TOMOGRAPHY