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The role of marrow transplantation in the eradication of malignant disease. [Dogs; /sup 60/Co]

Journal Article · · Cancer (Philadelphia); (United States)
This Kettering award lecture describes the history of bone marrow transplantation for treatment of disseminated malignant disease, leukemia, carried out at the University of Washington. A major problem after marrow grafting is the recurrence of leukemia and display of profound immunologic incompetence. Presently, marrow transplantation has become an accepted form of therapy for several types of human disease including malignant disease as well as hereditory diseases of the bone marrow.
Research Organization:
Univ. of Washington, Seattle
OSTI ID:
5238764
Journal Information:
Cancer (Philadelphia); (United States), Journal Name: Cancer (Philadelphia); (United States) Vol. 49:10; ISSN CANCA
Country of Publication:
United States
Language:
English

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Related Subjects

550900 -- Pathology
560151* -- Radiation Effects on Animals-- Man
560152 -- Radiation Effects on Animals-- Animals
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKYLATING AGENTS
ANIMAL CELLS
ANIMAL TISSUES
ANIMALS
ANTIGENS
ANTIMETABOLITES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BONE MARROW
COBALT 60
COBALT ISOTOPES
DIGESTIVE SYSTEM
DISEASES
DOGS
DRUGS
ELECTROMAGNETIC RADIATION
ENDOXAN
EXTERNAL IRRADIATION
GAMMA RADIATION
GASTROINTESTINAL TRACT
GLANDS
GRAFT-HOST REACTION
HEMATOPOIETIC SYSTEM
HEMIC DISEASES
IMMUNOSUPPRESSIVE DRUGS
IMMUNOTHERAPY
INTERFERON
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LETHAL IRRADIATION
LEUKEMIA
LIVER
MAMMALS
METHOTREXATE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGY
PATIENTS
RADIATIONS
RADIOISOTOPES
SKIN
SOMATIC CELLS
STEM CELLS
THERAPY
TISSUES
TRANSPLANTS
VERTEBRATES
WHOLE-BODY IRRADIATION
YEARS LIVING RADIOISOTOPES