The effect of zinc (Zn) supplementation during lactation on maternal Zn status and milk Zn concentrations

Conference · Thu Mar 14 23:00:00 EST 1991 · FASEB Journal (Federation of American Societies for Experimental Biology); (United States)

OSTI ID:5238488

Krebs, N F; Reidinger, C; Westcott, J L; Hartley, S; Hambidge, K M ^[1]

---

1. Univ. Colorado, Denver (United States)

The objective of this study was to longitudinally evaluate the effect of a dietary Zn supplement on maternal Zn states and milk Zn concentrations under a randomized, controlled, double-blinded study design. Sixty women, 30 {plus minus} 3.8 yrs, received either 15 mg Zn/day or placebo through {ge} 7 mos. of lactation. Dietary intake data, biochemical indices of Zn status and milk Zn concentrations were obtained at monthly intervals. Three day test-weighing was done at 2 wks and 3, 5, and 7 mos. Overall mean daily dietary intake for the non-Zn-supplemented group (n = 28) was 12.9 {plus minus} 2.2 mg, and for the Zn-supplemented group (n = 32), 25.7 {plus minus} 2.9 mg, including an average of 14 mg/d from a supplement. Plasma Zn concentrations did not differ between groups across lactation. Milk Zn concentrations were similar to those published previously and did not differ in monthly means or rate of decline according to group. Maternal Zn outputs to the infants at 2 wks and 3, 5 and 7 mos. were 2.17 {plus minus} 0.7, 0.92 {plus minus} 0.4, 0.72 {plus minus} 0.3, and 0.48 {plus minus} 0.26, respectively. The data suggest that average maternal Zn intake of {ge}10 mg/day during lactation is sufficient to maintain adequate maternal Zn status and milk Zn concentrations.

• OSTI ID: 5238488
• Report Number(s): CONF-9104107--
• Journal Information: FASEB Journal (Federation of American Societies for Experimental Biology); (United States), Journal Name: FASEB Journal (Federation of American Societies for Experimental Biology); (United States) Vol. 5:5; ISSN FAJOE; ISSN 0892-6638
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BODY FLUIDS
DIET
ELEMENTS
FEMALES
FOOD
INTAKE
LACTATION
MAMMALS
MAN
MATERIALS
METABOLISM
METALS
MILK
PRIMATES
VERTEBRATES
WOMEN
ZINC