Radionuclide imaging of the spleen with heat denatured technetium-99m RBC when the splenic reticuloendothelial system seems impaired

Journal Article · Tue Mar 01 00:00:00 EST 1988 · J. Nucl. Med.; (United States)

OSTI ID:5237690

Owunwanne, A; Halkar, R; Al-Rasheed, A; Abubacker, K C; Abdel-Dayem, H

Imaging of the spleen of 10 patients who had been hematologically diagnosed with sickle-cell anemia (SCA) was studied with (/sup 99m/Tc)tin colloid and heat denatured (/sup 99m/Tc)RBCs. In all ten patients, there was faint or nonvisualization of the spleen with (/sup 99m/Tc)tin colloid. However, with heat denatured (/sup 99m/Tc)RBCs, nine spleens were well visualized, and the uptake was homogenous. One spleen had two patchy areas of uptake. The results indicate that when splenic phagocytic function is impaired as reflected by nonvisualization of the spleen with (/sup 99m/Tc)tin colloid, it is still possible to image such a spleen with heat denatured (/sup 99m/Tc)RBCs

• Research Organization: Kuwait Univ.
• OSTI ID: 5237690
• Journal Information: J. Nucl. Med.; (United States), Vol. 29:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
SICKLE CELL ANEMIA
DIAGNOSIS
SPLEEN
RADIOISOTOPE SCANNING
COLLOIDS
COMPARATIVE EVALUATIONS
ERYTHROCYTES
HEAT
ISOMERIC NUCLEI
PATIENTS
PHAGOCYTOSIS
RETICULOENDOTHELIAL SYSTEM
TECHNETIUM 99
TIN
ANEMIAS
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
COUNTING TECHNIQUES
DISEASES
DISPERSIONS
ELEMENTS
ENERGY
HEMIC DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
METALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
SYMPTOMS
TECHNETIUM ISOTOPES
TISSUES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics