Effects of embryonic pre-exposure to methylmercury and Hg/sup 2 +/ on larval tolerance in Fundulus heteroclitus

Journal Article · Mon Oct 31 23:00:00 EST 1983 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01605470· OSTI ID:5213288

Weis, P ^[1]; Weis, J S

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1. Rutgers Univ., Newark, NJ

Many reports demonstrate enhanced metal tolerance as a result of previous exposure to low concentrations. Pretreatment of rainbow trout (Salmo gairdneri) eggs with cadmium made the larvae more resistant to subsequent Cd treatment. Larvae of the flagfish, Jordanella floridae, initially exposed as embryos to Zn and to mixtures of Zn and Cd were much more tolerant than those not previously exposed, indicating acclimation during embryonic exposure. Acclimation to metals after pre-exposure was attributed to stimulation of the synthesis of metal-binding proteins, or metallothioneins, in the liver, which form a nontoxic complex with the metal. In this paper we report on the effects of embryonic pre-exposure to methylmercury(meHf) and Hg/sup 2 +/ on larval susceptibility to these toxicants in the killifish, Fundulus heteroclitus.

• OSTI ID: 5213288
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 31:5; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL EFFECTS
BIOSYNTHESIS
ELEMENTS
FISHES
HYDROGEN COMPOUNDS
LARVAE
MERCURY
MERCURY COMPOUNDS
METALLOPROTEINS
METALLOTHIONEIN
METALS
METHYLMERCURY
ORGANIC COMPOUNDS
ORGANIC MERCURY COMPOUNDS
OXYGEN COMPOUNDS
PRENATAL EXPOSURE
PROTEINS
SEAWATER
SYNTHESIS
VERTEBRATES
WATER