Growth of and mineral deposition in young rats fed saturated and unsaturated fatty acids

Conference · Fri Mar 15 04:00:00 EST 1991 · FASEB Journal (Federation of American Societies for Experimental Biology); (United States)

OSTI ID:5213216

Magee, A; D'Souza, D ^[1]

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1. Univ. of North Carolina, Greensboro (United States) John Hopkins Univ., Baltimore, MD (United States)

Male weanling rats were used in 4 week experiments to study effects of saturated and unsaturated fatty acids on growth and mineral deposition in several organs (bone, kidneys, liver, spleen, testes). Minerals evaluated were calcium, copper, iron, magnesium, manganese, phosphorus, and zinc, and levels of these minerals in tests diets were appropriate for growing rats. Two levels of dietary fat were used, and fatty acids included in the study were butyric/capronic, palmitic/stearic, oleic, and linoleic/linolenic acids. Decreased weight gains were observed in rats fed saturated fatty acids or 10% fat, while increases in weight gains were associated with increases in polyunsaturated/saturated (P/S) ratios. Copper, iron, or zinc levels tended to be higher in organs of rats fed saturated fatty acids. P/S ratios had no effect on copper or zinc deposition, but decreases in liver iron and increases in spleen iron were observed in rats fed the higher P/S ratios. Manganese levels were generally unaffected by fatty acid types, fat level, or P/S ratio, although liver manganese levels were higher in rats fed unsaturated fatty acids. Dietary fatty acids, fat level, or P/S ratios had no apparent effects on calcium, magnesium, phosphorus, or zinc deposition in femurs and tibias of rats.

• OSTI ID: 5213216
• Report Number(s): CONF-9104107--
• Conference Information: Journal Name: FASEB Journal (Federation of American Societies for Experimental Biology); (United States) Journal Volume: 5:5
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH METALS
ANIMAL GROWTH
ANIMALS
BIOLOGICAL EFFECTS
CALCIUM
CARBOXYLIC ACIDS
COPPER
DISTRIBUTION
ELEMENTS
GROWTH
IRON
MAGNESIUM
MAMMALS
MANGANESE
METABOLISM
METALS
NONMETALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
PHOSPHORUS
RATS
RODENTS
TISSUE DISTRIBUTION
TRANSITION ELEMENTS
VERTEBRATES
ZINC