Estrogens and development

Journal Article · Sat Oct 31 23:00:00 EST 1987 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.877525· OSTI ID:5193868

McLachlan, J A; Newbold, R R

The normal development of the genital organs of mammals, including humans, is under hormonal control. A role for the female sex hormone estrogen in this process is still unclear. However, exposure of experimental animals or humans to the potent exogenous estrogen, diethylstilbestrol (DES), results in persistent differentiation effects. Since many chemicals in the environment are weakly estrogenic, the possibility of hormonally altered differentiation must be considered.

• Research Organization: National Institute of Environmental Health Sciences, Research Triangle Park, NC (USA)
• OSTI ID: 5193868
• Journal Information: Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 75; ISSN EVHPA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AROMATICS
BIOLOGICAL EFFECTS
BODY
CELL DIFFERENTIATION
ESTROGENS
FEMALE GENITALS
FEMALES
HORMONES
HYDROXY COMPOUNDS
MALE GENITALS
MAMMALS
MAN
ONTOGENESIS
ORGANIC COMPOUNDS
ORGANS
PHENOLS
PHYSIOLOGY
POLYPHENOLS
PRIMATES
REPRODUCTIVE DISORDERS
STEROID HORMONES
STILBESTROL
VERTEBRATES
WOMEN