Estrogens and development

Journal Article · Sun Nov 01 00:00:00 EST 1987 · Environ. Health Perspect.; (United States)

DOI:https://doi.org/10.1289/ehp.877525· OSTI ID:5193868

McLachlan, J A; Newbold, R R

The normal development of the genital organs of mammals, including humans, is under hormonal control. A role for the female sex hormone estrogen in this process is still unclear. However, exposure of experimental animals or humans to the potent exogenous estrogen, diethylstilbestrol (DES), results in persistent differentiation effects. Since many chemicals in the environment are weakly estrogenic, the possibility of hormonally altered differentiation must be considered.

• Research Organization: National Institute of Environmental Health Sciences, Research Triangle Park, NC (USA)
• OSTI ID: 5193868
• Journal Information: Environ. Health Perspect.; (United States), Vol. 75
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ESTROGENS
BIOLOGICAL EFFECTS
FEMALE GENITALS
ONTOGENESIS
MALE GENITALS
STILBESTROL
CELL DIFFERENTIATION
PHYSIOLOGY
REPRODUCTIVE DISORDERS
WOMEN
ANIMALS
AROMATICS
BODY
FEMALES
HORMONES
HYDROXY COMPOUNDS
MAMMALS
MAN
ORGANIC COMPOUNDS
ORGANS
PHENOLS
POLYPHENOLS
PRIMATES
STEROID HORMONES
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology